Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Viral hemorrhagic fevers (VHFs) represent a collection of illnesses caused by several distinct viral families. While some types of hemorrhagic fever viruses can cause relatively mild illnesses, many of these viruses cause life-threatening diseases. The chapters of this book discuss the consequences of the Ebola outbreak in West Africa; the most frequency imported infection worldwide (malaria); the reservoirs of selected infectious diseases (often bats and fruit bats); the clinical symptoms of viral diseases and the most widely used diagnostic methods for the correct identification of the patho

Hemorrhagic fever. --- Arenavirus diseases

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Arenavirus. --- Lymphocytic choriomeningitis virus. --- Lymphocytic choriomeningitis.

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne disease associated with severe hemorrhagic manifestations. CCHF has been referred to as the "Asian Ebola." However, in fact, the disease is one of the most widely distributed tick-borne diseases in the world, occurring in Africa, Asia, Europe, and the Middle East. This volume covers major aspects of this important disease and the virus which causes it. Chapters are written by leading experts in their fields and detail historical, public health, epidemiological, and clinical aspects of CCHF and the genetics and molecular biology of the virus. Additional chapters focus on disease control, tick vectors and infection among animals, both natural and experimental. This book will be of interest to virologists, microbiologists, medical entomologists, infectious disease physicians, epidemiologists, public health specialists, veterinary scientists, public health policy makers, journalists, and medical educators.

Hemorrhagic fever. --- Ticks as carriers of disease. --- Virus diseases. --- Viral diseases --- Viral infections --- Virus infections --- Communicable diseases --- Medical virology --- Pathogenic viruses --- Arachnida as carriers of disease --- Mites as carriers of disease --- Arenavirus diseases --- Medical virology. --- Bacteriology. --- Medical parasitology. --- Virology. --- Parasitology. --- Human beings --- Human parasitology --- Medical sciences --- Parasitology --- Parasitic diseases --- Microbiology --- Medical microbiology --- Virology --- Virus diseases --- Parasites --- Biology

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Lassa virus causes Lassa fever disease in several countries in West Africa, where it is estimated to infect up to half million people causing roughly five thousand deaths each year. This deadly virus has also been introduced in multiple occasions into the western world, including the United States, United Kingdom, Netherlands, Sweden, and Germany. Lassa virus infection, which is often misdiagnosed, can lead to a wide range of disease symptoms ranging from mild flu-like symptoms to bleeding disorders, multi-organ failure, and death. Despite some major discoveries made in recent years of research on Lassa fever, there are still many unresolved key issues that hamper the development of effective vaccines and therapies. Some of these issues include a detailed understanding of the viral and participating host factors in completing the virus life cycle, in mediating disease pathogenesis or protection, and in activating or suppressing host immune responses against virus infection. This book is devoted to understanding some of these important issues. Expert and timely contributions in the form of editorial and original research and review articles on Lassa fever viral replication, disease pathogenesis and protection, host immune modulations, and other related hot topics are presented in this publication.

Research & information: general --- Biology, life sciences --- Lassa virus disease (LVD) --- vaccine breadth --- mimicry --- B cell anergy --- conserved antigens --- Fc-gamma receptors --- conformational antigens --- broadly-neutralizing antibodies --- focused immunity --- dominant and subdominant epitopes --- cross-restriction --- Lassa virus --- Z protein --- late domain --- PPXY --- budding --- release --- matrix protein --- phosphorylation --- arenavirus --- mass spectrometry --- viral glycoprotein --- viral entry --- viral fusion --- fusion protein --- Lassa virus vaccine --- ML29 vaccine --- STAT-1-/- mice --- Mopeia virus --- interfering particles --- Lassa fever --- LASV --- virus–host interactions --- entry --- replication --- Lassa vaccine --- replication-deficient MVA vector --- VLP formation --- single-dose efficacy --- cell-mediated immunity --- arenaviruses --- viral hemorrhagic fevers --- animal models --- mammarenavirus --- vaccine --- virulence --- pathogenesis --- innate immunity --- adaptive immunity --- COVID-19

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Lassa virus causes Lassa fever disease in several countries in West Africa, where it is estimated to infect up to half million people causing roughly five thousand deaths each year. This deadly virus has also been introduced in multiple occasions into the western world, including the United States, United Kingdom, Netherlands, Sweden, and Germany. Lassa virus infection, which is often misdiagnosed, can lead to a wide range of disease symptoms ranging from mild flu-like symptoms to bleeding disorders, multi-organ failure, and death. Despite some major discoveries made in recent years of research on Lassa fever, there are still many unresolved key issues that hamper the development of effective vaccines and therapies. Some of these issues include a detailed understanding of the viral and participating host factors in completing the virus life cycle, in mediating disease pathogenesis or protection, and in activating or suppressing host immune responses against virus infection. This book is devoted to understanding some of these important issues. Expert and timely contributions in the form of editorial and original research and review articles on Lassa fever viral replication, disease pathogenesis and protection, host immune modulations, and other related hot topics are presented in this publication.

Lassa virus disease (LVD) --- vaccine breadth --- mimicry --- B cell anergy --- conserved antigens --- Fc-gamma receptors --- conformational antigens --- broadly-neutralizing antibodies --- focused immunity --- dominant and subdominant epitopes --- cross-restriction --- Lassa virus --- Z protein --- late domain --- PPXY --- budding --- release --- matrix protein --- phosphorylation --- arenavirus --- mass spectrometry --- viral glycoprotein --- viral entry --- viral fusion --- fusion protein --- Lassa virus vaccine --- ML29 vaccine --- STAT-1-/- mice --- Mopeia virus --- interfering particles --- Lassa fever --- LASV --- virus–host interactions --- entry --- replication --- Lassa vaccine --- replication-deficient MVA vector --- VLP formation --- single-dose efficacy --- cell-mediated immunity --- arenaviruses --- viral hemorrhagic fevers --- animal models --- mammarenavirus --- vaccine --- virulence --- pathogenesis --- innate immunity --- adaptive immunity --- COVID-19